Home >> News >> Senior scientist involved in stem cell scandal commits suicide in RIKEN

Senior scientist involved in stem cell scandal commits suicide in RIKEN

08-06-2014 11:22

Yoshiki Sasai, was confirmed dead on August 5th 2014, an apparent suicide in the RIKEN complex in Kobe, Japan. Sasai, 52, was a corresponding author on one of the papers and a co-author of the other. Together, they reported the discovery of a new phenomenon the researchers called stimulus-triggered acquisition of pluripotency (STAP) (http://inter-use.com/News/2014/0131/61.html).

The papers, whose lead author was Haruko Obokata, also of RIKEN CDB, appeared online in Nature on 29 January. After months of mounting claims of problems and a finding of research misconduct by Obokata by a RIKEN committee, Nature retracted the studies on 2 July (http://inter-use.com/News/2014/0702/69.html). The retraction notices cite duplicated and mixed-up images, mislabeling, faulty descriptions, and "inexplicable discrepancies in genetic background and transgene insertion sites between the donor mice and the reported" STAP cells.

To date, no other groups have succeeded in reproducing the work. RIKEN has a team attempting to determine what went wrong and conclusively determine if the STAP phenomenon is real. A separate committee has been charged with determining disciplinary measures for Obokata and her RIKEN co-authors and supervisors, including Sasai, although decisions have been put off pending the results of the ongoing investigation.

RIKEN posted a brief note in Japanese on its website confirming the death along with a statement expressing regret over the loss of an irreplaceable scientist from RIKEN President Ryoji Noyori.

Researchers were shocked and saddened by the news. "So very very sad! My sincere sympathy to Sasai's family. Community lost a great developmental biologist!" Kenneth Lee, a stem cell researcher at the Chinese University of Hong Kong, tweeted shortly after the news broke. “This is a tragedy and thoughts go out to his family, friends, and lab members,” wrote stem cell researcher Paul Knoepfler, of the University of California, Davis, School of Medicine in Sacramento, on his blog.

The above news comes from Science Insider (http://news.sciencemag.org/asiapacific/2014/08/senior-riken-scientist-involved-stem-cell-scandal-commits-suicide).

Copyright © 2013 International Union of Science & Education All rights reserved.